Lutetium-177 PSMA Therapy for Prostate Cancer (Pluvicto)



Targeted Treatment for Prostate Cancer: Pluvicto™


At The Urology Place, we want our patients to have access to the newest and most effective treatments for prostate cancer. Pluvicto™ is an FDA-approved therapy for men with advanced prostate cancer that has spread to other parts of the body and no longer responds to standard treatments.


Pluvicto works by finding a protein (called PSMA) that is commonly found on prostate cancer cells. Once it finds these cancer cells, it delivers a small amount of radiation directly to them, helping to kill the cancer while limiting damage to healthy cells.


Our team will guide you through every step of the process — from deciding if Pluvicto is right for you to monitoring your progress during treatment. We work closely with your other doctors to make sure you receive safe, personalized, and effective care.

Innovative Treatment for Prostate Cancer

Understanding Pluvicto

Who Qualifies For Pluvicto?


Pluvicto is designed for men with advanced prostate cancer that has spread to other parts of the body and is no longer responding to standard treatments like hormone therapy or chemotherapy.

To see if Pluvicto is right for you, doctors look for:

  • PSMA-positive cancer: This means your cancer cells have a protein called PSMA, which Pluvicto can target. A special scan (PSMA PET scan) is used to check this.
  • Previous treatments: Pluvicto is typically used after other standard therapies have been tried.
  • Overall health: Your doctor will review your health to make sure the treatment is safe for you.


Your urology and oncology team will review your medical history, scans, and lab results to determine if Pluvicto is a suitable option.

What Is The Mechanism Behind Pluvicto?


Pluvicto is a targeted therapy that helps fight advanced prostate cancer. It works by finding a protein called PSMA that is often found on prostate cancer cells. Once it attaches to these cells, Pluvicto delivers a small amount of radiation directly to the cancer, helping to kill it while leaving most healthy cells unharmed.


This targeted approach allows doctors to treat cancer that has spread, while minimizing side effects compared to traditional treatments. Your care team at The Urology Place will guide you through the treatment process and monitor your progress every step of the way.

Understanding Pluvicto Side Effects

Pluvicto is a targeted therapy used in the treatment of certain urologic conditions. While it can be effective, it's important to be aware of potential side effects. Common side effects may include fatigue, nausea, and changes in appetite. More serious effects can occur, so monitoring and communication with your healthcare provider are essential.

  • What are the common side effects of Pluvicto?

    Patients often report fatigue, nausea, and loss of appetite. These effects can vary in intensity and duration.

  • Are there serious side effects to watch for?

    Yes, some patients may experience more severe reactions such as allergic reactions or significant changes in blood counts. It's crucial to report any unusual symptoms to your doctor immediately.

  • How can side effects be managed?

    Managing side effects often involves supportive care, such as hydration and dietary adjustments. Your healthcare team can provide personalized strategies to help alleviate discomfort.

  • When should I contact my doctor?

    If you experience severe side effects or any new symptoms that concern you, reach out to your healthcare provider right away for guidance.

  • Can side effects change over time?

    Yes, side effects can evolve as treatment progresses. Regular check-ins with your healthcare provider can help manage these changes effectively.
Follow-Up Care

Understanding Your Follow-Up Period During Pluvicto Treatment

After starting Pluvicto treatment, it's essential to have regular follow-up appointments to monitor your progress and manage any side effects. These visits allow our team at The Urology Place to assess how well the treatment is working and make any necessary adjustments to your care plan. Typically, follow-ups are scheduled every few weeks, but the exact timing may vary based on your individual response to the treatment.

What to Expect During Follow-Ups

During your follow-up visits, we will conduct various tests and evaluations to ensure that the treatment is effective. This may include blood tests, imaging studies, and discussions about any symptoms you may be experiencing. Our goal is to provide personalized care tailored to your needs.
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Managing Side Effects

It's important to communicate any side effects you may encounter during your treatment. Our team is here to help you manage these effects effectively, ensuring that your treatment journey is as comfortable as possible. We will discuss strategies to alleviate any discomfort and improve your overall well-being.
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Importance of Adherence

Sticking to your treatment schedule and attending follow-up appointments is crucial for the success of your Pluvicto therapy. Consistent monitoring helps us catch any issues early and adjust your treatment as needed, maximizing the benefits of your care.
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Your Support System

Having a support system in place can make a significant difference during your treatment. Whether it's family, friends, or support groups, sharing your experiences and feelings can help you navigate this journey more effectively. Remember, you are not alone, and we are here to support you every step of the way.
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Your Health Matters

At The Urology Place, we prioritize your well-being. Understanding the side effects of treatments like Pluvicto is crucial for effective management. Our team is here to support you every step of the way.